Where does a migraine attack originate? In the brainstem
Migraine is a common, paroxysmal, highly disabling primary headache disorder. The origin of migraine attacks is enigmatic. Numerous clinical and experimental results suggest that the activation of distinct brainstem nuclei is crucial in its pathogenesis, but the primary cause of this activation is n...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
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Springer-Verlag
2012
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| Sorozat: | JOURNAL OF NEURAL TRANSMISSION
119 No. 5 |
| doi: | 10.1007/s00702-012-0788-9 |
| mtmt: | 1968870 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/9880 |
| Tartalmi kivonat: | Migraine is a common, paroxysmal, highly disabling primary headache disorder. The origin of migraine attacks is enigmatic. Numerous clinical and experimental results suggest that the activation of distinct brainstem nuclei is crucial in its pathogenesis, but the primary cause of this activation is not fully understood. We conclude that the initialization of a migraine attack can be explained as an altered function of the neuronal elements of the brainstem nuclei. In light of our findings and the literature data, we can assume that migraine is a subcortical disorder of a specific brainstem area. |
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| Terjedelem/Fizikai jellemzők: | 557-568 |
| ISSN: | 0300-9564 |