Unique cardiac Purkinje fiber transient outward current β-subunit composition a potential molecular link to idiopathic ventricular fibrillation. /
These results point to a previously unknown central role of DPP6 in PF I(to), with DPP6 gain of function selectively enhancing PF current, and suggest that a DPP6-mediated PF early-repolarization syndrome might be a novel molecular paradigm for some forms of idiopathic ventricular fibrillation.
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Dokumentumtípus: | Cikk |
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2013-05-10
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Sorozat: | Circulation research
112 No. 10 |
doi: | 10.1161/CIRCRESAHA.112.300227 |
mtmt: | 2244228 |
Online Access: | http://publicatio.bibl.u-szeged.hu/9040 |
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024 | 7 | |a 10.1161/CIRCRESAHA.112.300227 |2 doi | |
024 | 7 | |a 2244228 |2 mtmt | |
040 | |a SZTE Publicatio Repozitórium |b hun | ||
041 | |a zxx | ||
100 | 1 | |a Xiao Ling | |
245 | 1 | 0 | |a Unique cardiac Purkinje fiber transient outward current β-subunit composition |h [elektronikus dokumentum] : |b a potential molecular link to idiopathic ventricular fibrillation. / |c Xiao Ling |
260 | |c 2013-05-10 | ||
300 | |a 1310-22 | ||
490 | 0 | |a Circulation research |v 112 No. 10 | |
520 | 3 | |a These results point to a previously unknown central role of DPP6 in PF I(to), with DPP6 gain of function selectively enhancing PF current, and suggest that a DPP6-mediated PF early-repolarization syndrome might be a novel molecular paradigm for some forms of idiopathic ventricular fibrillation. | |
700 | 0 | 1 | |a Koopmann Tamara T. |e aut |
700 | 0 | 1 | |a Ördög Balázs |e aut |
700 | 0 | 1 | |a Postema Pieter G. |e aut |
700 | 0 | 1 | |a Verkerk Arie O. |e aut |
700 | 0 | 1 | |a Iyer Vivek |e aut |
700 | 0 | 1 | |a Sampson Kevin J. |e aut |
700 | 0 | 1 | |a Boink Gerard J. J. |e aut |
700 | 0 | 1 | |a Mamarbachi Maya A. |e aut |
700 | 0 | 1 | |a Varró András |e aut |
700 | 0 | 1 | |a Jordaens Luc |e aut |
700 | 0 | 1 | |a Res Jan |e aut |
700 | 0 | 1 | |a Kass Robert S. |e aut |
700 | 0 | 1 | |a Wilde Arthur A. |e aut |
700 | 0 | 1 | |a Bezzina Connie R. |e aut |
700 | 0 | 1 | |a Nattel Stanley |e aut |
856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/9040/7/2244228.pdf |z Dokumentum-elérés |