DermAll nanomedicine for allergen-specific immunotherapy
A novel allergen-specific immunotherapy for IgE-mediated allergies is presented in this paper, using an experimental allergic rhinitis model and a synthetic plasmid pDNA/PEIm nanomedicine expressing ovalbumin as model allergen. Over 50% reduction of symptoms was found as the immune system's bal...
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Dokumentumtípus: | Cikk |
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Elsevier
2013-11
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Sorozat: | Nanomedicine: Nanotechnology, Biology and Medicine
9 No. 8 |
doi: | 10.1016/j.nano.2013.05.011 |
mtmt: | 2397277 |
Online Access: | http://publicatio.bibl.u-szeged.hu/4073 |
Tartalmi kivonat: | A novel allergen-specific immunotherapy for IgE-mediated allergies is presented in this paper, using an experimental allergic rhinitis model and a synthetic plasmid pDNA/PEIm nanomedicine expressing ovalbumin as model allergen. Over 50% reduction of symptoms was found as the immune system's balance was favorably altered toward more TH2-polarized immune responses. |
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Terjedelem/Fizikai jellemzők: | 1245-1254 |
ISSN: | 1549-9634 |