Attentional modulation of perceptual organisation in schizophrenia
INTRODUCTION: Previous studies indicated impaired perceptual organisation in schizophrenia. This study investigated lateral connection and attentional modulation in early visual cortex of schizophrenia patients. METHODS: Contrast threshold was measured for a central Gabor patch, flanked with orthogo...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2009
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| Sorozat: | COGNITIVE NEUROPSYCHOLOGY
14 No. 2 |
| Tárgyszavak: | |
| doi: | 10.1080/13546800902757936 |
| mtmt: | 1340882 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/37823 |
| Tartalmi kivonat: | INTRODUCTION: Previous studies indicated impaired perceptual organisation in schizophrenia. This study investigated lateral connection and attentional modulation in early visual cortex of schizophrenia patients. METHODS: Contrast threshold was measured for a central Gabor patch, flanked with orthogonal and collinear Gabor patches. In the attended condition, participants performed a concurrent vernier task by determining the spatial offset of the flankers. RESULTS: The controls (n=25) had lower contrast thresholds in the collinear condition than in the orthogonal condition, whereas the schizophrenia patients (n=43) did not benefit from the presence of collinear flankers. This deficit was not ameliorated by attentional modulation. Antipsychotic medication did not affect the performance. CONCLUSIONS: These results suggest that lateral connections are impaired in early visual cortex of schizophrenia patients. This deficit cannot be restored by top-down attentional modulation of target-flanker interactions. |
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| Terjedelem/Fizikai jellemzők: | 77-86 |
| ISSN: | 0264-3294 |