Analysis of Anaerobes and Some Other Fastidious Bacteria
Anaerobes, like some other fastidious, slow-growing bacteria belonging to the HACEK group have special place among human pathogenic bacteria. They are important pathogens, however, owing to their special requirements to be isolated from clinical samples, such as strict anaerobic or CO2-rich environm...
Elmentve itt :
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| Dokumentumtípus: | Könyv része |
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Caister Academic Press
Norfolk (VA)
2016
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| Sorozat: | MALDI-TOF mass spectormetry in microbiology
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| Tárgyszavak: | |
| doi: | 10.21775/9781910190418.02 |
| mtmt: | 32102969 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/34963 |
| Tartalmi kivonat: | Anaerobes, like some other fastidious, slow-growing bacteria belonging to the HACEK group have special place among human pathogenic bacteria. They are important pathogens, however, owing to their special requirements to be isolated from clinical samples, such as strict anaerobic or CO2-rich environment for their long incubation time, makes their identification time-consuming. In this chapter several applications of the mass spectrometry will be discussed beside the rapid identification of these bacteria. It has been shown since the first studies that the database developments are mandatory including not only reference strains of the different well-known or newly accepted species, but including the mass spectra of well-characterized clinical isolates may improve the performance of the MALDI-TOF MS identification of these bacteria. Mass spectrometry-based typing of Bacteroides fragilis strains may help to detect clinical isolates belonging to division II, which harbour resistance gene against carbapenems. Propionibacterium acnes phylotypes could also be distinguished by looking for peak variations of the mass spectra of the isolates belonging to this species. Direct identification of anaerobic bacteria from positive blood cultures should be evaluated further as well as the possibilities to use MALDI-TOF MS for antibiotic resistance determination of these bacteria. |
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| Terjedelem/Fizikai jellemzők: | 15 33-47 |
| ISBN: | 9781910190418 |