Site-directed allostery perturbation to probe the negative regulation of hypoxia inducible factor-1α
The interaction between the intrinsically disordered transcription factor HIF-1α and the coactivator proteins p300/CBP is essential in the fast response to low oxygenation. The negative feedback regulator, CITED2, switches off...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2024
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| Sorozat: | RSC CHEMICAL BIOLOGY
5 No. 8 |
| Tárgyszavak: | |
| doi: | 10.1039/D4CB00066H |
| mtmt: | 34901238 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/34823 |
| Tartalmi kivonat: | The interaction between the intrinsically disordered transcription factor HIF-1α and the coactivator proteins p300/CBP is essential in the fast response to low oxygenation. The negative feedback regulator, CITED2, switches off... |
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| Terjedelem/Fizikai jellemzők: | 711-720 |
| ISSN: | 2633-0679 |