Chemotaxis of freshly separated and cultured human keratinocytes

It is generally accepted that keratinocyte migration plays a critical role in the process of wound healing. A study was therefore made of the migratory response of freshly separated and cultured human keratinocytes to factors with chemotactic properties for a variety of cells. Interleukin-1alpha (IL...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Gyulai Rolland Péter
Hunyadi János
Kenderessy Szabó Anna
Kemény Lajos
Dobozy Attila
Dokumentumtípus: Cikk
Megjelent: 1994
Sorozat:CLINICAL AND EXPERIMENTAL DERMATOLOGY 19 No. 4
Tárgyszavak:
doi:10.1111/j.1365-2230.1994.tb01201.x

mtmt:105842
Online Access:http://publicatio.bibl.u-szeged.hu/31958
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520 3 |a It is generally accepted that keratinocyte migration plays a critical role in the process of wound healing. A study was therefore made of the migratory response of freshly separated and cultured human keratinocytes to factors with chemotactic properties for a variety of cells. Interleukin-1alpha (IL-1alpha), interferon-gamma (IFN-gamma), interleukin-8 (IL-8), and tumour necrosis factor alpha (TNF-alpha) were tested for their chemotactic effectiveness in a modified Boyden chamber assay. IFN-gamma, IL-1alpha and IL-8 were demonstrated to serve as chemoattractants for freshly separated keratinocytes. For cultured cells, however, only IFN-gamma was found to display chemotactic properties. The findings demonstrate that there is significant difference between the chemotactic behaviour of freshly separated and cultured cells. 
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700 0 1 |a Hunyadi János  |e aut 
700 0 2 |a Kenderessy Szabó Anna  |e aut 
700 0 2 |a Kemény Lajos  |e aut 
700 0 2 |a Dobozy Attila  |e aut 
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