The Impact of Specialised Heart Failure Outpatient Care on the Long-Term Application of Guideline-Directed Medical Therapy and on Prognosis in Heart Failure with Reduced Ejection Fraction

The Impact of Specialised Heart Failure Outpatient Care on the Long-Term Application of Guideline-Directed Medical Therapy and on Prognosis in Heart Failure with Reduced Ejection Fraction

(1) Background: Besides the use of guideline-directed medical therapy (GDMT), multidisciplinary heart failure (HF) outpatient care (HFOC) is of strategic importance in HFrEF. (2) Methods: Data from 257 hospitalised HFrEF patients between 2019 and 2021 were retrospectively analysed. Application and t...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Muk Balázs
Bánfi-Bacsárdi Fanni
Vámos Máté
Pilecky Dávid
Majoros Zsuzsanna
Török Gábor Márton
Vágány Dénes
Polgár Balázs
Solymossi Balázs
Borsányi Tünde Dóra
Andréka Péter
Duray Gábor Zoltán
Kiss Róbert Gábor
Dékány Miklós
Nyolczas Noémi
Dokumentumtípus: Cikk
Megjelent: 2024
Sorozat:DIAGNOSTICS 14 No. 2
Tárgyszavak:
Klinikai orvostan
doi:10.3390/diagnostics14020131

mtmt:34483467
Online Access:http://publicatio.bibl.u-szeged.hu/29226
Leíró adatok
Tartalmi kivonat:(1) Background: Besides the use of guideline-directed medical therapy (GDMT), multidisciplinary heart failure (HF) outpatient care (HFOC) is of strategic importance in HFrEF. (2) Methods: Data from 257 hospitalised HFrEF patients between 2019 and 2021 were retrospectively analysed. Application and target doses of GDMT were compared between HFOC and non-HFOC patients at discharge and at 1 year. 1-year all-cause mortality (ACM) and rehospitalisation (ACH) rates were compared using the Cox proportional hazard model. The effect of HFOC on GDMT and on prognosis after propensity score matching (PSM) of 168 patients and the independent predictors of 1-year ACM and ACH were also evaluated. (3) Results: At 1 year, the application of RASi, MRA and triple therapy (TT: RASi + βB + MRA) was higher (p < 0.05) in the HFOC group, as was the proportion of target doses of ARNI, βB, MRA and TT. After PSM, the composite of 1-year ACM or ACH was more favourable with HFOC (propensity-adjusted HR = 0.625, 95% CI = 0.401–0.974, p = 0.038). Independent predictors of 1-year ACM were age, systolic blood pressure, application of TT and HFOC, while 1-year ACH was influenced by the application of TT. (4) Conclusions: HFOC may positively impact GDMT use and prognosis in HFrEF even within the first year of its initiation.
Terjedelem/Fizikai jellemzők:16
ISSN:2075-4418

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