Epidemiology and clinical features of SARS-CoV-2 infection in hospitalized children across four waves in Hungary A retrospective, comparative study from March 2020 to December 2021 /

Background and AimsFrom 2019 till the present, infections induced by the novel coronavirus and its mutations have posed a new challenge for healthcare. However, comparative studies on pediatric infections throughout waves are few. During four different pandemic waves, we intended to investigate the...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Takács Andrea Tímea
Bukva Mátyás
Gavallér Gabriella
Kapus Katalin
Rózsa Mária
Bán-Gagyi Boglárka
Sinkó Mária
Szűcs Dániel
Terhes Gabriella
Bereczki Csaba
Dokumentumtípus: Cikk
Megjelent: 2022
Sorozat:Health Science Reports 5 No. 6
Tárgyszavak:
doi:10.1002/hsr2.937

mtmt:33314398
Online Access:http://publicatio.bibl.u-szeged.hu/25818
Leíró adatok
Tartalmi kivonat:Background and AimsFrom 2019 till the present, infections induced by the novel coronavirus and its mutations have posed a new challenge for healthcare. However, comparative studies on pediatric infections throughout waves are few. During four different pandemic waves, we intended to investigate the clinical and epidemiological characteristic of the pediatric population hospitalized for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection. MethodsBetween March 2020 and December 2021, we performed our retrospective research on children infected with the SARS-CoV-2 virus at the University of Szeged. We analyzed the data of all patients who required hospitalization due to positive results of SARS-CoV-2 tests (Nucleic Acid Amplification Test or rapid antigen test). Data analysis included demographic data, medical history, clinical findings, length of hospitalization, and complications, using medical records. ResultsIn this study, data from 358 coronavirus-infected children were analyzed. The most affected age group was children over 1 month and under 1 year (30.2%). The highest number of cases was recorded in the fourth wave (53.6%). Fever (65.6%), cough (51.4%), nasal discharge (35.3%), nausea and vomiting (31.3%), and decreased oral intake (28.9%) were the most common symptoms. The most common complications were dehydration (50.5%), pneumonia (14.9%), and bronchitis/bronchiolitis (14.5%). Based on RR values, there are considerable differences in the prevalence of the symptoms and complications between the different age groups and waves. Cox proportional hazard model analyzes showed that fever and tachypnoea had a relevant effect on days to recovery. ConclusionsWe found trends similar to those previously published, overall statistics. The proportion of children requiring hospitalization varied from wave to wave, with the fourth wave affecting the Hungarian child population the most. Our findings suggest that hospitalization time is unrelated to age, but that certain symptoms (fever and tachypnoea) are associated with longer hospitalization. The onset of certain symptoms may differ by age group.
Terjedelem/Fizikai jellemzők:11
ISSN:2398-8835