The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease

The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of...

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Bibliographic Details
Main Authors: Inczefi Orsolya
Bacsur Péter
Resál Tamás
Keresztes Csilla
Molnár Tamás
Format: Article
Published: 2022
Series:FRONTIERS IN NUTRITION 9
Subjects:
doi:10.3389/fnut.2022.718710

mtmt:32835309
Online Access:http://publicatio.bibl.u-szeged.hu/24671
Description
Summary:The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of cancer, and neuropsychiatric disorders. In this study, the mechanisms leading to dysbiosis and "leaky gut" are reviewed, and a short summary of the current knowledge regarding different diseases is provided. The simplest way to restore intestinal permeability and the microbiota could be ideal nutrition. Further therapeutic options are also available, such as the administration of probiotics or postbiotics or fecal microbiota transplantation.
Physical Description:Terjedelem: 15-Azonosító: 718710
ISSN:2296-861X