Does inflammatory bowel disease have different characteristics according to stage of adolescence?

There is a lack of data about demographic and treatment characteristics of adolescent patients with inflammatory bowel disease (IBD). The aim of this retrospective, epidemiological study was to evaluate characteristics and therapeutic features of Hungarian adolescents with IBD.We analysed the social...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Szántó Kata Judit
Balázs Tamás
Mihonné Schrempf Dóra
Farkas Klaudia
Molnár Tamás
Dokumentumtípus: Cikk
Megjelent: 2021
Sorozat:THERAPEUTIC ADVANCES IN GASTROENTEROLOGY 14
doi:10.1177/1756284820986670

mtmt:32114390
Online Access:http://publicatio.bibl.u-szeged.hu/21954
Leíró adatok
Tartalmi kivonat:There is a lack of data about demographic and treatment characteristics of adolescent patients with inflammatory bowel disease (IBD). The aim of this retrospective, epidemiological study was to evaluate characteristics and therapeutic features of Hungarian adolescents with IBD.We analysed the social security databases of the National Health Insurance Fund. Adolescent patients with IBD for whom data from 2009 to 2016 were observable in the database were enrolled. Patients aged 14 to 17 years and 18 to 21 years were defined as middle and late adolescent patients.The incidences of IBD were 20.12 per 100,000 middle adolescent patients and 29.72 per 100,000 late adolescent patients. Admission to gastroenterology department was higher in both groups compared with admissions to surgery department. Mesalazine was used by a high proportion of Crohn's disease and ulcerative colitis patients. Rates of corticosteroid use were similar in both groups, with a tendency to decrease over time. The need for biologic agents was higher in the middle adolescent patients. The proportion of patients in the middle adolescent group who received anti-TNF therapy showed an increasing tendency.Our data suggest differences in the treatment strategies of gastroenterologists for these age groups. The greater need of anti-TNF therapy among the middle adolescent group indicates that adolescent patients before the transition to adult care may have a more severe disease phenotype. We expect that a strategy of early, effective treatment will significantly ameliorate the subsequent disease course, which is manifested in adult care.
Terjedelem/Fizikai jellemzők:Terjedelem: 10-Azonosító: 1756284820986670
ISSN:1756-283X