Honfoglalók származásának és rokonsági viszonyainak vizsgálata archaeogenetikai módszerekkel
In the last few decades genetic analysis has been playing an increasing role in tracing the origin and relation of human populations. DNA sequences isolated from ancient human remains can be used, to unravel ancestor-descendant relationships between populations and reconstruct population histor...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2017
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| Sorozat: | ANTHROPOLOGIAI KÖZLEMÉNYEK
58 |
| doi: | 10.20330/AnthropKozl.2017.58.91 |
| mtmt: | 3304520 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/20972 |
| Tartalmi kivonat: | In the last few decades genetic analysis has been playing an increasing role in tracing the origin and relation of human populations. DNA sequences isolated from ancient human remains can be used, to unravel ancestor-descendant relationships between populations and reconstruct population history. In our research we successfully optimized ancient DNA extraction methods and adapted the latest haplotyping methods. We complemented the traditional PCR based HVR sequencing method with the SNaPshot assay, which is used to determine 22 haplotype defining SNP-s in the mtDNA coding region. In the case of bone samples with best DNA preservation the same method could also be used to determine the paternal (Y chromosome) haplogroup. In the last few years the next generation sequencing method (NGS) has revolutionized the aDNA field, by providing reliable high quality sequence reads, and enabling to sequence even whole ancient genomes. Recently we have adapted the NGS method in our lab (Archoegenetic Laboratory, University of Szeged) and sequenced whole mtDNA genomes from a large number of Hungarian conqueror samples. Some 40% of the conquerors had East-Central Asian origin, other 60% of the samples had best matches with modern people from Europe. |
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| Terjedelem/Fizikai jellemzők: | 91-95 |
| ISSN: | 0003-5440 |