Endoscopic and surgical drainage for pancreatic fluid collections are better than percutaneous drainage Meta-analysis /
Background Pancreatic pseudocyst (PP) and walled-off necrosis can be managed endoscopically, percutaneously or surgically, but with diverse efficacy. Aims & methods A comprehensive literature search was carried out from inception to December 2018, to identify articles which compared at least tw...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2020
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| Sorozat: | PANCREATOLOGY
20 No. 1 |
| doi: | 10.1016/j.pan.2019.10.006 |
| mtmt: | 30881472 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/18127 |
| Tartalmi kivonat: | Background Pancreatic pseudocyst (PP) and walled-off necrosis can be managed endoscopically, percutaneously or surgically, but with diverse efficacy. Aims & methods A comprehensive literature search was carried out from inception to December 2018, to identify articles which compared at least two of the three kinds of treatment modalities, regarding the mortality, clinical success, recurrence, complications, cost and length of hospitalisation (LOH). Results The outcomes of endoscopic (ED) and percutaneous drainage (PD) were comparable in six articles. The clinical success of endoscopic intervention was better considering any types of fluid collections (OR = 3.36; 95% confidence interval (CI) 1.48, 7.63; p = 0.004). ED was preferable regarding recurrence of PP (OR = 0.23; 95% CI 0.08, 0.66; p = 0.006). Fifteen articles compared surgical intervention with ED. Significant difference was found in postoperative LOH (WMD (days) = −4.61; 95%CI -7.89, −1.33; p = 0.006) and total LOH (WMD (days) = −3.67; 95%CI -5.00, −2.34; p < 0.001) which favored endoscopy, but ED had lower rate of clinical success (OR = 0.54; 95% CI 0.35, 0.85; p = 0.007) and higher rate of recurrence (OR = 1.80; 95% CI 1.16, 2.79; p = 0.009) in the treatment of PP. Eleven studies compared surgical and percutaneous intervention. PD resulted in higher rate of recurrence (OR = 4.91; 95% CI 1.82, 13.22; p = 0.002) and lower rate of clinical success (OR = 0.13; 95% CI 0.07, 0.22, p < 0.001). Conclusion Both endoscopy and surgery are preferable over percutaneous intervention, furthermore endoscopic treatment is associated with shorter hospitalisation than surgery. |
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| Terjedelem/Fizikai jellemzők: | 132-141 |
| ISSN: | 1424-3903 |