Synthesis of Fluorine-Containing Molecular Entities Through Fluoride Ring Opening of Oxiranes and Aziridines
The current minireview highlights the most relevant methodologies for the creation of fluorinated scaffolds accessed through transformations of three-membered heterocycles (oxiranes and aziridines) involving their opening with various nucleophilic fluorinating agents reported over recent years. The...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2019
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| Sorozat: | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
2019 No. 33 |
| doi: | 10.1002/ejoc.201900981 |
| mtmt: | 30929734 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/17870 |
| Tartalmi kivonat: | The current minireview highlights the most relevant methodologies for the creation of fluorinated scaffolds accessed through transformations of three-membered heterocycles (oxiranes and aziridines) involving their opening with various nucleophilic fluorinating agents reported over recent years. The purpose of the review is also to provide an overview of the ring-opening synthetic practices with fluoride towards different functionalized, fluorine-containing scaffolds with the focus on regioselectivity/regiocontrol and enantioselectivity including symmetric or unsymmetric monoheterocycles, cycloalkane-fused oxiranes and aziridines. |
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| Terjedelem/Fizikai jellemzők: | 5574-5602 |
| ISSN: | 1434-193X |