The effect of serum triglyceride concentration on the outcome of acute pancreatitis
Elevated serum triglyceride concentration (seTG, >1.7 mM or >150 mg/dL) or in other words hypertriglyceridemia (HTG) is common in the populations of developed countries. This condition is accompanied by an increased risk for various diseases, such as acute pancreatitis (AP). It has been propos...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2018
|
| Sorozat: | SCIENTIFIC REPORTS
8 No. 1 |
| doi: | 10.1038/s41598-018-32337-x |
| mtmt: | 3422217 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/15411 |
| LEADER | 02413nab a2200361 i 4500 | ||
|---|---|---|---|
| 001 | publ15411 | ||
| 005 | 20190508150527.0 | ||
| 008 | 190508s2018 hu o 0|| angol d | ||
| 022 | |a 2045-2322 | ||
| 024 | 7 | |a 10.1038/s41598-018-32337-x |2 doi | |
| 024 | 7 | |a 3422217 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a angol | ||
| 100 | 1 | |a Kiss Lóránd | |
| 245 | 1 | 4 | |a The effect of serum triglyceride concentration on the outcome of acute pancreatitis |h [elektronikus dokumentum] / |c Kiss Lóránd |
| 260 | |c 2018 | ||
| 300 | |a Azonosító: 14096-Terjedelem: 14 p | ||
| 490 | 0 | |a SCIENTIFIC REPORTS |v 8 No. 1 | |
| 520 | 3 | |a Elevated serum triglyceride concentration (seTG, >1.7 mM or >150 mg/dL) or in other words hypertriglyceridemia (HTG) is common in the populations of developed countries. This condition is accompanied by an increased risk for various diseases, such as acute pancreatitis (AP). It has been proposed that HTG could also worsen the course of AP. Therefore, in this meta-analysis, we aimed to compare the effects of various seTGs on the severity, mortality, local and systemic complications of AP, and on intensive care unit admission. 16 eligible studies, including 11,965 patients were retrieved from PubMed and Embase. The results showed that HTG significantly elevated the odds ratio (OR = 1.72) for severe AP when compared to patients with normal seTG (<1.7 mM). Furthermore, a significantly higher occurrence of pancreatic necrosis, persistent organ failure and renal failure was observed in groups with HTG. The rates of complications and mortality for AP were significantly increased in patients with seTG >5.6 mM or >11.3 mM versus <5.6 mM or <11.3 mM, respectively. We conclude that the presence of HTG worsens the course and outcome of AP, but we found no significant difference in AP severity based on the extent of HTG. | |
| 700 | 0 | 1 | |a Fűr Gabriella |e aut |
| 700 | 0 | 1 | |a Mátrai Péter |e aut |
| 700 | 0 | 1 | |a Hegyi Péter |e aut |
| 700 | 0 | 1 | |a Ivány Emese |e aut |
| 700 | 0 | 1 | |a Szabó Imre |e aut |
| 700 | 0 | 1 | |a Habon Tamás |e aut |
| 700 | 0 | 1 | |a Alizadeh Hussain |e aut |
| 700 | 0 | 1 | |a Gyöngyi Zoltán |e aut |
| 700 | 0 | 1 | |a Vigh Éva |e aut |
| 700 | 0 | 1 | |a Erőss Bálint Mihály |e aut |
| 700 | 0 | 1 | |a Erős Adrienn |e aut |
| 700 | 0 | 1 | |a Czakó László |e aut |
| 700 | 0 | 1 | |a Rakonczay Zoltán, ifj. |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/15411/1/3422217.pdf |z Dokumentum-elérés |