Molecular analysis of the carbapenem and metronidazole resistance mechanisms of Bacteroides strains reported in a Europe-wide antibiotic resistance survey
Here we examine the carbapenem and metronidazole resistance mechanisms of 640 Bacteroides strains reported in the 2008-2009 European antibiotic susceptibility survey. Of the 22 strains with elevated imipenem minimum inhibitory concentrations (≥4 μg/mL), 10 were cfiA-positive and out of these 5 carri...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2013
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| Sorozat: | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
41 No. 2 |
| doi: | 10.1016/j.ijantimicag.2012.10.001 |
| mtmt: | 2196925 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/13013 |
| LEADER | 02171nab a2200277 i 4500 | ||
|---|---|---|---|
| 001 | publ13013 | ||
| 005 | 20200310094416.0 | ||
| 008 | 180226s2013 hu o 0|| zxx d | ||
| 022 | |a 0924-8579 | ||
| 024 | 7 | |a 10.1016/j.ijantimicag.2012.10.001 |2 doi | |
| 024 | 7 | |a 2196925 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a zxx | ||
| 100 | 1 | |a Sóki József | |
| 245 | 1 | 0 | |a Molecular analysis of the carbapenem and metronidazole resistance mechanisms of Bacteroides strains reported in a Europe-wide antibiotic resistance survey |h [elektronikus dokumentum] / |c Sóki József |
| 260 | |c 2013 | ||
| 300 | |a 122-125 | ||
| 490 | 0 | |a INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS |v 41 No. 2 | |
| 520 | 3 | |a Here we examine the carbapenem and metronidazole resistance mechanisms of 640 Bacteroides strains reported in the 2008-2009 European antibiotic susceptibility survey. Of the 22 strains with elevated imipenem minimum inhibitory concentrations (≥4 μg/mL), 10 were cfiA-positive and out of these 5 carried activating insertion sequence (IS) elements in the upstream regions of the cfiA genes. However, resistant strains with cfiA genes but with no activating IS elements were found (n = 2) as well as a resistant strain with no cfiA gene. In the former the resistance phenotypes by Etest were heterogeneous, whilst in the latter no carbapenemase production was seen; both mechanisms have been rarely observed, examined and characterised. Interestingly, few (n = 3) nim-positive strains were found, including one metronidazole- resistant strain harbouring nimE activated by ISBf6, and two susceptible strains harbouring chromosomally located nim genes. © 2012 Elsevier B.V. and the International Society of Chemotherapy. | |
| 700 | 0 | 1 | |a Eitel Zsuzsa |e aut |
| 700 | 0 | 2 | |a Zsoldiné Urbán Edit |e aut |
| 700 | 0 | 2 | |a Nagy Erzsébet |e aut |
| 700 | 0 | 2 | |a ESCMID Study Group on Anaerobic Infections |e aut |
| 700 | 0 | 2 | |a Terhes Gabriella |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/13013/1/1_s2.0_S0924857912003858_main_u.pdf |z Dokumentum-elérés |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/13013/7/antimicrobial_agents_2013_41_002_editoral.pdf |z Dokumentum-elérés |