Emergence of OXA-162-producing Klebsiella pneumoniae in Hungary.
Abstract In August 2012, 2 carbapenem-resistant Klebsiella pneumoniae isolates from the University of Szeged were submitted to the National Reference Laboratory at the National Centre for Epidemiology to confirm the carbapenem resistance mechanism. PCR assays and sequencing revealed that the isolate...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
Taylor and Francis
2014
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| Sorozat: | SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
46 No. 4 |
| doi: | 10.3109/00365548.2013.879993 |
| mtmt: | 2562278 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/12182 |
| Tartalmi kivonat: | Abstract In August 2012, 2 carbapenem-resistant Klebsiella pneumoniae isolates from the University of Szeged were submitted to the National Reference Laboratory at the National Centre for Epidemiology to confirm the carbapenem resistance mechanism. PCR assays and sequencing revealed that the isolates harboured the blaOXA-162 carbapenemase gene, a very recently described variant of OXA-48, and the blaCTX-M-15 extended-spectrum beta-lactamase gene. The isolates had indistinguishable PFGE patterns and belonged to sequence type ST15. To the best of our knowledge, this is the first description of OXA-48-like carbapenemase-producing bacteria in Hungary and of an OXA-162-type carbapenemase gene in the K. pneumoniae ST15 clone. |
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| Terjedelem/Fizikai jellemzők: | 320-324 |
| ISSN: | 0036-5548 |