Effect of a nitric oxide donor on nitroxergic nerve fibers in the rat dura mater
Nitroglycerine, given subcutaneously to rats (10 mg/kg body weight) induces increased beading of nitric oxide synthase immunoreactive (NOS-IR) nerve fibers in the supratentorial cerebral dura mater, and an apparent increase in the number of NOS-IR nerve fibers in the dural areas supplied by the ante...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
1999
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| Sorozat: | NEUROSCIENCE LETTERS
260 No. 2 |
| doi: | 10.1016/S0304-3940(98)00949-5 |
| mtmt: | 1032259 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/10539 |
| Tartalmi kivonat: | Nitroglycerine, given subcutaneously to rats (10 mg/kg body weight) induces increased beading of nitric oxide synthase immunoreactive (NOS-IR) nerve fibers in the supratentorial cerebral dura mater, and an apparent increase in the number of NOS-IR nerve fibers in the dural areas supplied by the anterior and middle meningeal arteries, and the sinus sagittalis superior. Structural alterations of nitroxergic axons innervating blood vessels of the dura mater support the idea that nitric oxide is involved in the induction of headache also by a primary peripheral action, a well-known side effect of coronary dilator agents. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved. |
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| Terjedelem/Fizikai jellemzők: | 97-100 |
| ISSN: | 0304-3940 |