Adverse effects of dopamine potentiation by long-term treatment with selegiline
A patient with triosephosphate isomerase (TPI) deficiency exhibited worsening of abnormal involuntary movements of the dystonic type and developed psychiatric symptoms while on selegiline. When selegiline was stopped after 9 years of treatment, abnormal involuntary movements improved to pretreatment...
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Dokumentumtípus: | Cikk |
Megjelent: |
2004
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Sorozat: | MOVEMENT DISORDERS
19 No. 1 |
doi: | 10.1002/mds.10641 |
mtmt: | 1032213 |
Online Access: | http://publicatio.bibl.u-szeged.hu/10113 |
Tartalmi kivonat: | A patient with triosephosphate isomerase (TPI) deficiency exhibited worsening of abnormal involuntary movements of the dystonic type and developed psychiatric symptoms while on selegiline. When selegiline was stopped after 9 years of treatment, abnormal involuntary movements improved to pretreatment level and psychiatric behaviour returned to normal. Monoamine oxidase-B platelet activity was low in this patient. (C) 2003 Movement Disorder Society. |
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Terjedelem/Fizikai jellemzők: | 107-109 |
ISSN: | 0885-3185 |