A neurohypophysis and adenohypophysis model for the investigation of deponated chemical environmental loads
Persistent organic pollutants, chemicals with high chemical stability and low degradability, widely used in industry and/or agriculture. A heterogeneous group of these compounds include chlorobenzenes (ClB), which are deposited in the lipophilic phases of living organisms and induce dose-dependent t...
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| Dokumentumtípus: | Könyv része |
| Megjelent: |
University of Szeged
Szeged
2024
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
30 |
| Kulcsszavak: | Biokémia, Környezetkémia, Toxikológia, Molekuláris biológia |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/85755 |
| LEADER | 02161naa a2200313 i 4500 | ||
|---|---|---|---|
| 001 | acta85755 | ||
| 005 | 20241127092753.0 | ||
| 008 | 241127s2024 hu o 100 eng d | ||
| 020 | |a 978-963-688-009-5 | ||
| 040 | |a SZTE Egyetemi Kiadványok Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Molnár Zsolt | |
| 245 | 1 | 2 | |a A neurohypophysis and adenohypophysis model for the investigation of deponated chemical environmental loads |h [elektronikus dokumentum] / |c Molnár Zsolt |
| 260 | |a University of Szeged |b Szeged |c 2024 | ||
| 300 | |a 341-345 | ||
| 490 | 0 | |a Proceedings of the International Symposium on Analytical and Environmental Problems |v 30 | |
| 520 | 3 | |a Persistent organic pollutants, chemicals with high chemical stability and low degradability, widely used in industry and/or agriculture. A heterogeneous group of these compounds include chlorobenzenes (ClB), which are deposited in the lipophilic phases of living organisms and induce dose-dependent toxic effects in the cells of affected tissues. The aim of this study was to monitor the effects of different doses of ClB treatments on changes in energy transfer (Mg2+- ATPase) and protein production of neurohypophysis and adenohypophysis. Male Wistar rats were treated with ClB (1:1 mixture of hexachlorobenzene and 1,2,4-trichlorobenzene) in a dose of 1.0 and 10.0 µg /b.w. kg through a gastric tube. Rats were exposed to ClB for 30, 60, and 90 days. The results showed that ClB exposures significantly increased energy transfer and protein production in cell cultures. | |
| 650 | 4 | |a Természettudományok | |
| 650 | 4 | |a Kémiai tudományok | |
| 650 | 4 | |a Biológiai tudományok | |
| 695 | |a Biokémia, Környezetkémia, Toxikológia, Molekuláris biológia | ||
| 700 | 0 | 1 | |a Kiss Péter Sándor |e aut |
| 700 | 0 | 1 | |a Mózes Miklós |e aut |
| 700 | 0 | 1 | |a Radács Marianna |e aut |
| 700 | 0 | 1 | |a Hausinger Péter |e aut |
| 700 | 0 | 1 | |a Sepp Krisztián |e aut |
| 700 | 0 | 1 | |a Gálfi Márta |e aut |
| 711 | |a 30th International Symposium on Analytical and Environmental Problems |c Szeged |d 2024. október 7-8. | ||
| 856 | 4 | 0 | |u http://acta.bibl.u-szeged.hu/85755/1/proceedings_of_isaep_2024_341-345.pdf |z Dokumentum-elérés |