Vacuum-ultraviolet photolysis of non-steroidal anti-inflammatory drugs
Non-steroidal anti-inflammatory drugs (NSAIDs) ibuprofen, ketoprofen, diclofenac and naproxen are detected even in natural waters. Their degradation was achieved through the generation of reactive oxygen containing species (ROS, such as *OH, 1102* and •O2’) by using a xenon excimer lamp (Xmax. = 172...
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| Corporate Author: | |
| Format: | Book part |
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SZAB
Szeged
2012
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| Series: | Proceedings of the International Symposium on Analytical and Environmental Problems
17 |
| Kulcsszavak: | Gyógyszerkémia, Analitikai kémia |
| Subjects: | |
| Online Access: | http://acta.bibl.u-szeged.hu/76391 |
| Summary: | Non-steroidal anti-inflammatory drugs (NSAIDs) ibuprofen, ketoprofen, diclofenac and naproxen are detected even in natural waters. Their degradation was achieved through the generation of reactive oxygen containing species (ROS, such as *OH, 1102* and •O2’) by using a xenon excimer lamp (Xmax. = 172 ± 14 nm). The effect of the initial drug concentration, dissolved molecular oxygen, methanol as *OH scavenger and the effect of these pharmaceuticals on each other were investigated. According to the results, not only the reactions based on *OH, but the reactions with other ROS and excited water molecules should also be taken under consideration for the interpretation of the transformation of the four investigated NSAIDs. |
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| Physical Description: | 64-67 |
| ISBN: | 978-963-315-066-5 |