2-OXO-1,2,3,4-tetrahydropyrimidine-azo-pyridone dye a potential application as new green-emitting fluorescent probe /

Molecular imaging is a relatively new research field, which has demonstrated great potential, especially in clinical oncology – from drug development to cancer early detection. The key of fluorescence imaging is the construction of fluorescent probe which is composed of two parts, the recognition gr...

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Bibliographic Details
Main Authors: Tadić Julijana
Janković Nenad
Lađarević Jelena
Porobić Slavica
Kojić Marija
Marinović-Cincović Milena
Mijn Dušan
Corporate Author: International Symposium on Analytical and Environmental Problems (27.) (2021) (Szeged)
Format: Book part
Published: University of Szeged Szeged 2021
Series:Proceedings of the International Symposium on Analytical and Environmental Problems 27
Kulcsszavak:Kémia
Subjects:
Online Access:http://acta.bibl.u-szeged.hu/75997
Description
Summary:Molecular imaging is a relatively new research field, which has demonstrated great potential, especially in clinical oncology – from drug development to cancer early detection. The key of fluorescence imaging is the construction of fluorescent probe which is composed of two parts, the recognition groups to recognize cancer cells, and fluorophores to signal the recognition events. In this research, the structure of new fluorescent azo dye based on 2-oxo-1,2,3,4-tetrahydropyrimidin and 2-pyridone moieties has been reported. The absorption and emission properties of the investigated azo dye have been studied using UV-Vis and fluorescence spectroscopy. The obtained results suggest that studied dye meets the requirements for new green-emitting fluorescent probe, suitable for further application in biomedical researches.
Physical Description:324-326
ISBN:978-963-306-835-9