Transport study of kynurenic acid and its newest derivatives through and in vitro model of the blood-brain barrier using targeted UHPLC-MS\MS
We have developed a targeted UHPLC-ESI–MS/MS method for the quantification of kynurenic acid (KYNA) and its derivatives from biological samples. The samples were gained from in vitro permeability assay. We have found that the transportation of the derivatives through the blood-brain barrier is bette...
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| Testületi szerző: | |
| Dokumentumtípus: | Könyv része |
| Megjelent: |
2020
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
26 |
| Kulcsszavak: | Biofizika, Fizikai kémia |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/74049 |
| LEADER | 01401naa a2200265 i 4500 | ||
|---|---|---|---|
| 001 | acta74049 | ||
| 005 | 20220808153923.0 | ||
| 008 | 211118s2020 hu o 1|| eng d | ||
| 020 | |a 978-963-306-771-0 | ||
| 040 | |a SZTE Egyetemi Kiadványok Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Kmetykó Noémi | |
| 245 | 1 | 0 | |a Transport study of kynurenic acid and its newest derivatives through and in vitro model of the blood-brain barrier using targeted UHPLC-MS\MS |h [elektronikus dokumentum] / |c Kmetykó Noémi |
| 260 | |c 2020 | ||
| 300 | |a 404-405 | ||
| 490 | 0 | |a Proceedings of the International Symposium on Analytical and Environmental Problems |v 26 | |
| 520 | 3 | |a We have developed a targeted UHPLC-ESI–MS/MS method for the quantification of kynurenic acid (KYNA) and its derivatives from biological samples. The samples were gained from in vitro permeability assay. We have found that the transportation of the derivatives through the blood-brain barrier is better than KYNA. | |
| 650 | 4 | |a Természettudományok | |
| 650 | 4 | |a Kémiai tudományok | |
| 695 | |a Biofizika, Fizikai kémia | ||
| 700 | 0 | 1 | |a Wilhelm Imola |e aut |
| 700 | 0 | 1 | |a Ilisz István |e aut |
| 700 | 0 | 1 | |a Berkecz Róbert |e aut |
| 710 | |a International Symposium on Analytical and Environmental Problems (26.) (2020) (Szeged) | ||
| 856 | 4 | 0 | |u http://acta.bibl.u-szeged.hu/74049/1/proceedings_of_isaep_2020_404-405.pdf |z Dokumentum-elérés |