Microwave-assisted phospha-Michael addition reactions on 13αestrane core
Novel 16-modified 13 α-estrone derivatives were synthesized via phospha-Michael addition reactions. Transformations of steroidal α,β-unsaturated ketons were carried out under different conditions in a microwave (MW) reactor. The antiproliferative activities of the newly synthesized compounds against...
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| Dokumentumtípus: | Könyv része |
| Megjelent: |
2020
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
26 |
| Kulcsszavak: | Kémia |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/73989 |
| LEADER | 01612naa a2200301 i 4500 | ||
|---|---|---|---|
| 001 | acta73989 | ||
| 005 | 20220808153923.0 | ||
| 008 | 211117s2020 hu o 1|| eng d | ||
| 020 | |a 978-963-306-771-0 | ||
| 040 | |a SZTE Egyetemi Kiadványok Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Jójárt Rebeka | |
| 245 | 1 | 0 | |a Microwave-assisted phospha-Michael addition reactions on 13αestrane core |h [elektronikus dokumentum] / |c Jójárt Rebeka |
| 260 | |c 2020 | ||
| 300 | |a 177-178 | ||
| 490 | 0 | |a Proceedings of the International Symposium on Analytical and Environmental Problems |v 26 | |
| 520 | 3 | |a Novel 16-modified 13 α-estrone derivatives were synthesized via phospha-Michael addition reactions. Transformations of steroidal α,β-unsaturated ketons were carried out under different conditions in a microwave (MW) reactor. The antiproliferative activities of the newly synthesized compounds against a range of human adherent cancer cell lines (SCC-131, SCC154, Hela, SiHa, C33A, A2780, MCF-7, MDA-MB-231, T47D) were investigated by means of MTT assays. Certain potent derivatives were identified. | |
| 650 | 4 | |a Természettudományok | |
| 650 | 4 | |a Kémiai tudományok | |
| 695 | |a Kémia | ||
| 700 | 0 | 1 | |a Kóczán Lili |e aut |
| 700 | 0 | 1 | |a Fajka Lilla |e aut |
| 700 | 0 | 1 | |a Bartha Sándor |e aut |
| 700 | 0 | 1 | |a Minorics Renáta |e aut |
| 700 | 0 | 1 | |a Zupkó István |e aut |
| 700 | 0 | 1 | |a Mernyák Erzsébet |e aut |
| 710 | |a International Symposium on Analytical and Environmental Problems (26.) (2020) (Szeged) | ||
| 856 | 4 | 0 | |u http://acta.bibl.u-szeged.hu/73989/1/proceedings_of_isaep_2020_177-178.pdf |z Dokumentum-elérés |