Possible neurotoxicity of titanium dioxide nanoparticles in a subacute rat model

Titanium dioxide nanoparticles (TiO2 NPs) have many industrial applications and also appear in various consumers’ goods including foods and medicines. This widespread application raises the question of a potential occupational, environmental and/or intentional human exposure and health hazard. Motil...

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Bibliographic Details
Main Authors: Horváth Tamara
Vezér Tünde
Papp András
Corporate Author: International Symposium on Analytical and Environmental Problems (21.) (2015) (Szeged)
Format: Book part
Published: 2015
Series:Proceedings of the International Symposium on Analytical and Environmental Problems 21
Kulcsszavak:Kísérleti állatok, Közegészségügy
Online Access:http://acta.bibl.u-szeged.hu/56004
Description
Summary:Titanium dioxide nanoparticles (TiO2 NPs) have many industrial applications and also appear in various consumers’ goods including foods and medicines. This widespread application raises the question of a potential occupational, environmental and/or intentional human exposure and health hazard. Motility of NPs within the organism and surface reactivity of TiO2 NPs suggests, among others, potential nervous system tixicity. In the present work, rats were intratracheally exposed to TiO2 NPs and functional changes in the nervous system were examined using electrophysiological, behavioural and biochemical methods. The results verified to some extent the neurotoxicity of nano-titanium but also underlined the need for further investigations.
Physical Description:368-372
ISBN:978-963-306-411-5