Image processing-based automatic pupillometry on infrared videos

Pupillometry is a non-invasive technique that can be used to objectively characterize pathophysiological changes involving the pupillary reflex. It is essentially the measurement of the pupil diameter over time. Here, specially designed computer algorithms provide fast, reliable and reproducible sol...

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Bibliographic Details
Main Authors: Kalmár György
Büki Alexandra
Kékesi Gabriella
Horváth Gyöngyi
Nyúl László G.
Format: Article
Published: 2017
Series:Acta cybernetica 23 No. 2
Kulcsszavak:Képfeldolgozás - digitális, Képszerkesztés, Infravörös spektroszkópia, Színképelemzés, Pupillometria, Infravörös sugárzás
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doi:10.14232/actacyb.23.2.2017.10

Online Access:http://acta.bibl.u-szeged.hu/50090
Description
Summary:Pupillometry is a non-invasive technique that can be used to objectively characterize pathophysiological changes involving the pupillary reflex. It is essentially the measurement of the pupil diameter over time. Here, specially designed computer algorithms provide fast, reliable and reproducible solutions for the analysis. These methods use a priori information about the shape and color of the pupil. Our study focuses on measuring the diameter and dynamics of the pupils of rats with schizophrenia using videos recorded with a modified digital camera under infrared (IR) illumination. We developed a novel, robust method that measures the size of a pupil even under poor circumstances (noise, blur, reflections and occlusions). We compare our results with measurements obtained using manual annotation.
Physical Description:599-613
ISSN:0324-721X