Anticancer thiosemicarbazones chemical properties, interaction with iron metabolism, and resistance development /

Heffeter Petra, Pape Veronika, Enyedy Éva Anna, Keppler Bernhard K., Szakács Gergely, Kowol Christian R.
2019

Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs

Mathuber Marlene, Schueffl Hemma, Dömötör Orsolya, Karnthaler Claudia, Enyedy Éva Anna, Heffeter Petra, Kowol Christian R.
2020

Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones synthesis, solution equilibrium and bioactivity /

Kowol Christian R., Nagy Nóra Veronika, Jakusch Tamás, Roller Alexander, Heffeter Petra, Keppler Bernhard K., Enyedy Éva Anna
2015

Complex formation and cytotoxicity of Triapine derivatives a comparative solution study on the effect of the chalcogen atom and NH-methylation /

Enyedy Éva Anna, May Nóra Veronika, Pape Veronika, Heffeter Petra, Szakács Gergely, Keppler Bernhard K., Kowol Christian R.
2020

Synthesis and biological evaluation of biotin-conjugated anticancer thiosemicarbazones and their iron(III) and copper(II) complexes

Kallus Sebastian, Uhlik Lukas, van Schoonhoven Sushilla, Pelivan Karla, Berger Walter, Enyedy Éva Anna, Hofmann Thilo, Heffeter Petra, Kowol Christian R., Keppler Bernhard K.
2019

Impact of stepwise NH2-methylation of Triapine on the physico-chemical properties, anticancer activity and resistance circumvention

Kowol Christian R., Walter Miklós, Pfaff Sarah, Hager Sonja, Kallus Sebastian, Pelivan Karla, Kubanik Mario, Enyedy Éva Anna, Berger Walter, Heffeter Petra, Keppler Bernhard K.
2016

Triapine and a more potent dimethyl derivative induce ER stress in cancer cells

Trondl Robert, Flocke Lea S., Kowol Christian R., Heffeter Petra, Jungwirth Ute, Mair Georg E., Steinborn Ralf, Enyedy Éva Anna, Jakupec Michael A., Berger Walter, Keppler Bernhard K.
2014

Maleimide-functionalised platinum(IV) complexes as synthetic platform for targeted drug delivery

Pichler Verena, Mayr Josef, Heffeter Petra, Dömötör Orsolya, Enyedy Éva Anna, Hermann Gerrit, Groza Diana, Köllensperger Gunda, Galanksi Markus, Berger Walter, Keppler Bernhard K., Kowol Christian R.
2013

Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Eff...

Bormio Nunes Julia H., Hager Sonja, Mathuber Marlene, Pósa Vivien, Roller Alexander, Enyedy Éva Anna, Stefanelli Alessia, Berger Walter, Keppler Bernhard K., Heffeter Petra, Kowol Christian R.
2020

High copper complex stability and slow reduction kinetics as key parameters for improved activity, paraptosis induction and impact on drug-resistant cells of anticancer thiosemicar...

Hager Sonja, Pape Veronika, Pósa Vivien, Montsch Bianca, Uhlik Lukas, Szakács Gergely, Tóth Szilárd, Jabronka Nikolett, Keppler Bernhard K., Kowol Christian R., Enyedy Éva Anna, Heffeter Petra
2020

Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance

Pósa Vivien, Stefanelli Alessia, Nunes Julia H. Bormio, Hager Sonja, Mathuber Marlene, May Nóra Veronika, Berger Walter, Keppler Bernhard K., Kowol Christian R., Enyedy Éva Anna, Heffeter Petra
2022