Are the metal identity and stoichiometry of metal complexes important for colchicine site binding and inhibition of tubulin polymerization?

Besleaga Iuliana, Raptová Renáta, Stoica Alexandru-Constantin, Milunović Miljan N.M, Zalibera Michal, Bai Ruoli, Igaz Nóra, Reynisson Johannes, Csontné Kiricsi Mónika, Enyedy Éva Anna, Rapta Peter, Hamel Ernest, Arion Vladimir
2024

Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells

Ohui Kateryna, Stepanenko Iryna, Besleaga Iuliana, Babak Maria V., Stafi Radu, Darvasiova Denisa, Giester Gerald, Pósa Vivien, Enyedy Éva Anna, Végh Dániel, Rapta Péter, Ang Wee Han, Popović-Bijelić Ana, Arion Vladimir B.
2020

Triapine Analogues and Their Copper(II) Complexes Synthesis, Characterization, Solution Speciation, Redox Activity, Cytotoxicity, and mR2 RNR Inhibition /

Besleaga Iuliana, Stepanenko Iryna, Petrasheuskaya Tatsiana, Darvasiova Denisa, Breza Martin, Hammerstad Marta, Marć Małgorzata A., Prado-Roller Alexander, Spengler Gabriella, Popovic-Bijelic Ana, Enyedy Éva Anna, Rapta Peter, Shutalev Anatoly D., Arion Vladimir B.
2021

Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubu...

Milunovic Miljan N. M., Ohui Katerina, Besleaga Iuliana, Petrasheuskaya Tatsiana V., Dömötör Orsolya, Enyedy Éva Anna, Darvasiova Denisa, Rapta Peter, Barbieriková Zuzana, Vegh Daniel, Tóth Szilárd, Tóth Judit, Kucsma Nóra, Szakács Gergely, Popović-Bijelić Ana, Zafar Ayesha, Reynisson Jóhannes, Shutalev Anatoly D., Bai Ruoli, Hamel Ernest, Arion Vladimir B.
2024