Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus
The neuroprotective effect Of L-kynurenine sulfate (KYN), a precursor of kynurenic acid (KYNA, a selective N-methyl-D-aspartate receptor antagonist), was studied. KYN (300 mg/kg i.p., applied daily for 5 days) appreciably decreased the number of injured pyramidal cells from 1850 +/- 100/mm(2) to 100...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2008
|
| Sorozat: | NEUROBIOLOGY OF DISEASE
32 No. 2 |
| doi: | 10.1016/j.nbd.2008.07.013 |
| mtmt: | 1174679 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/9974 |