GM1 controlled lateral segregation of tyrosine kinase Lck predispose T-cells to cell-derived galectin-1-induced apoptosis
One prominent immunoregulatory function of galectin-1 (Gal-1), a beta-galactoside binding mammalian lectin, is induction of apoptosis in activated T-cells by a process depending on the activity of Src family tyrosine kinase, Lck. Although the requirement for Lck in Gal-1 induced T-cell death and the...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2014
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| Sorozat: | MOLECULAR IMMUNOLOGY
57 No. 2 |
| doi: | 10.1016/j.molimm.2013.10.010 |
| mtmt: | 2459241 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/9663 |