Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates
Cation-π interactions to cognate ligands in enzymes have key roles in ligand binding and enzymatic catalysis. We have deciphered the key functional role of both charged and aromatic residues within the choline binding subsite of CTP:phosphocholine cytidylyltransferase and choline kinase from Plasmod...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2014-12-01
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| Sorozat: | Angewandte Chemie (International ed. in English)
53 No. 49 |
| doi: | 10.1002/anie.201408246 |
| mtmt: | 2737826 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/7707 |