A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro /
Abstract Pluchea odorata is ethno pharmaceutically used to treat inflammation-associated disorders. The dichloromethane extract (DME) was tested in the carrageenan-induced rat paw oedema assay investigating its effect on inflammation that was inhibited by 37%. Also an in vitro anti-neoplastic potent...
Elmentve itt :
Szerzők: |
Blaschke Michael McKinnon Ruxandra Huu Chi Nguyen Holzner Silvio Zehl Martin Atanasov Atanas Georgiev Schelch Karin Krieger Sigurd Diaz Rene Frisch Richard Feistel Björn Jäger Walter Ecker Gerhard F Dirsch Verena M Grusch Michael Zupkó István Urban Ernst Kopp Brigitte Krupitza Georg |
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Dokumentumtípus: | Cikk |
Megjelent: |
Elsevier
2015
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Sorozat: | MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
777 |
doi: | 10.1016/j.mrfmmm.2015.04.011 |
mtmt: | 2890601 |
Online Access: | http://publicatio.bibl.u-szeged.hu/6938 |
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