Synthesis of antiproliferative 13α-d-homoestrones via Lewis acid-promoted one-pot Prins–Ritter reactions of d-secosteroidal δ-alkenyl-aldehydes
Abstract A simple one-pot Prins–Ritter route was developed for the synthesis of 16-acylamino-17a-hydroxy-d-homoestrone 3-benzyl and 3-methyl ethers in the 13α-estrone series. The d-secosteroidal δ-alkenyl-aldehydes were allowed to react with different nitriles in the presence of BF3·OEt2 as a Lewis...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2015
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| Sorozat: | STEROIDS
102 |
| doi: | 10.1016/j.steroids.2015.07.004 |
| mtmt: | 2932883 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/6934 |