Different administration schedules of darbepoetin alfa affect oxidized and reduced glutathione levels to a similar extent in 5/6 nephrectomized rats

Different administration schedules of darbepoetin alfa affect oxidized and reduced glutathione levels to a similar extent in 5/6 nephrectomized rats

Our results suggest that the extent of oxidative stress is similar in response to different dosing regimens of DA in 5/6 NX rats when comparable hemoglobin levels are maintained. These findings remain to be confirmed in chronic kidney disease patients.

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Bibliographic Details
Main Authors: Monostori Péter
Kocsis-Fodor Gabriella
Ökrös Zsuzsanna
Bencsik Péter
Czétényi Orsolya
Kiss Zoltán
Gellén Balázs
Bereczki Csaba
Ocsovszki Imre
Pipis Judit
Pálóczi János
Sárközy Márta
Török Szilvia
Szőllősiné Varga Ilona
Kiss István
Fodor Eszter
Csont Tamás Bálint
Ferdinandy Péter
Túri Sándor
Format: Article
Published: 2013-08
Series:Clinical and experimental nephrology 17 No. 4
doi:10.1007/s10157-012-0749-5

mtmt:2161782
Online Access:http://publicatio.bibl.u-szeged.hu/6595
Description
Summary:Our results suggest that the extent of oxidative stress is similar in response to different dosing regimens of DA in 5/6 NX rats when comparable hemoglobin levels are maintained. These findings remain to be confirmed in chronic kidney disease patients.
Physical Description:569-574
ISSN:1437-7799

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