Epigenetic Regulatory Processes Involved in the Establishment and Maintenance of Skin Homeostasis—The Role of Microbiota

Epigenetic mechanisms are central to the regulation of all biological processes. This manuscript reviews the current understanding of diverse epigenetic modifications and their role in the establishment and maintenance of normal skin functions. In healthy skin, these mechanisms allow for the precise...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Szabó Kornélia Ágnes
Balogh Fanni
Romhányi Dóra
Erdei Lilla
Toldi Blanka
Gyulai Rolland Péter
Kemény Lajos
Groma Gergely
Dokumentumtípus: Cikk
Megjelent: 2025
Sorozat:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 26 No. 2
Tárgyszavak:
doi:10.3390/ijms26020438

mtmt:35678432
Online Access:http://publicatio.bibl.u-szeged.hu/39248
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520 3 |a Epigenetic mechanisms are central to the regulation of all biological processes. This manuscript reviews the current understanding of diverse epigenetic modifications and their role in the establishment and maintenance of normal skin functions. In healthy skin, these mechanisms allow for the precise control of gene expression, facilitating the dynamic balance between cell proliferation and differentiation necessary for effective barrier function. Furthermore, as the skin ages, alterations in epigenetic marks can lead to impaired regenerative capacity and increased susceptibility to environmental stressors. The interaction between skin microbiota and epigenetic regulation will also be explored, highlighting how microbial communities can influence skin health by modulating the host gene expression. Future research should focus on the development of targeted interventions to promote skin development, resilience, and longevity, even in an ever-changing environment. This underscores the need for integrative approaches to study these complex regulatory networks. 
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700 0 1 |a Balogh Fanni  |e aut 
700 0 1 |a Romhányi Dóra  |e aut 
700 0 1 |a Erdei Lilla  |e aut 
700 0 1 |a Toldi Blanka  |e aut 
700 0 1 |a Gyulai Rolland Péter  |e aut 
700 0 1 |a Kemény Lajos  |e aut 
700 0 1 |a Groma Gergely  |e aut 
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