Platelet-Rich Plasma in Chronic Wound Management A Systematic Review and Meta-Analysis of Randomized Clinical Trials /
Background: Chronic wounds place a heavy burden on the healthcare system due to the prolonged, continuous need for human resources for wound management. Our aim was to investigate the therapeutic effects of platelet-rich plasma on the treatment of chronic wounds. Methods: The systematic literature s...
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2022
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| Sorozat: | JOURNAL OF CLINICAL MEDICINE
11 No. 24 |
| Tárgyszavak: | |
| doi: | 10.3390/jcm11247532 |
| mtmt: | 33369810 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/36955 |
| LEADER | 02312nab a2200301 i 4500 | ||
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| 024 | 7 | |a 10.3390/jcm11247532 |2 doi | |
| 024 | 7 | |a 33369810 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Meznerics Fanni Adél | |
| 245 | 1 | 0 | |a Platelet-Rich Plasma in Chronic Wound Management |h [elektronikus dokumentum] : |b A Systematic Review and Meta-Analysis of Randomized Clinical Trials / |c Meznerics Fanni Adél |
| 260 | |c 2022 | ||
| 300 | |a 15 | ||
| 490 | 0 | |a JOURNAL OF CLINICAL MEDICINE |v 11 No. 24 | |
| 520 | 3 | |a Background: Chronic wounds place a heavy burden on the healthcare system due to the prolonged, continuous need for human resources for wound management. Our aim was to investigate the therapeutic effects of platelet-rich plasma on the treatment of chronic wounds. Methods: The systematic literature search was performed in four databases. Randomized clinical trials reporting on patients with chronic wounds treated with platelet-rich plasma (PRP) were included, comparing PRP with conventional ulcer therapy. We pooled the data using the random effects model. Our primary outcome was the change in wound size. Results: Our systematic search provided 2688 articles, and we identified 48 eligible studies after the selection and citation search. Thirty-three study groups of 29 RCTs with a total of 2198 wounds showed that the odds for complete closure were significantly higher in the PRP group than in the control group (OR = 5.32; CI: 3.37; 8.40; I2 = 58%). Conclusion: PRP is a safe and effective modality to enhance wound healing. By implementing it in clinical practice, platelet-rich plasma could become a widely used, valuable tool as it could not only improve patients’ quality of life but also decrease the healthcare burden of wound management. | |
| 650 | 4 | |a Általános orvostudomány | |
| 700 | 0 | 1 | |a Fehérvári Péter |e aut |
| 700 | 0 | 1 | |a Dembrovszky Fanni |e aut |
| 700 | 0 | 1 | |a Kovács Kata Dorottya |e aut |
| 700 | 0 | 1 | |a Kemény Lajos Vince |e aut |
| 700 | 0 | 1 | |a Csupor Dezső |e aut |
| 700 | 0 | 1 | |a Hegyi Péter |e aut |
| 700 | 0 | 1 | |a Bánvölgyi András |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/36955/1/jcm-11-07532-v2.pdf |z Dokumentum-elérés |