Left atrial function during exercise stress echocardiography as a sign of paroxysmal/persistent atrial fibrillation

Atrial cardiomyopathy is closely associated with atrial fibrillation (AF), and some patients exhibit no dysfunction at rest but demonstrate evident changes in left atrial (LA) function and LA volume during exercise. This study aimed to identify distinguishing signs during exercise stress echocardiog...

Full description

Saved in:
Bibliographic Details
Main Authors: Zagatina Angela
Ciampi Quirino
Peteiro Jesus Vazquez
Kalinina Elena
Begidova Irina
Padang Ratnasari
Boshchenko Alla
Merli Elisa
Lisi Matteo
Rodriguez-Zanella Hugo
Kobal Sergio
Ágoston Gergely
Varga Albert
Wierzbowska-Drabik Karina
Kasprzak Jarosław D
Arbucci Rosina
Zhuravleva Olga
Čelutkienė Jelena
Lowenstein Jorge
Ratanasit Nithima Chaowalit
Colonna Paolo
Carerj Scipione
Pepi Mauro
Pellikka Patricia A
Picano Eugenio
Kollaborációs szervezet: Stress Echo 2030 study group
Pálinkás Attila
Sepp Róbert
Pálinkás Eszter Dalma
Format: Article
Published: 2024
Series:CARDIOVASCULAR ULTRASOUND 22 No. 1
Subjects:
doi:10.1186/s12947-024-00332-0

mtmt:35526278
Online Access:http://publicatio.bibl.u-szeged.hu/35119
LEADER 03491nab a2200553 i 4500
001 publ35119
005 20241112123052.0
008 241112s2024 hu o 000 eng d
022 |a 1476-7120 
024 7 |a 10.1186/s12947-024-00332-0  |2 doi 
024 7 |a 35526278  |2 mtmt 
040 |a SZTE Publicatio Repozitórium  |b hun 
041 |a eng 
100 1 |a Zagatina Angela 
245 1 0 |a Left atrial function during exercise stress echocardiography as a sign of paroxysmal/persistent atrial fibrillation  |h [elektronikus dokumentum] /  |c  Zagatina Angela 
260 |c 2024 
300 |a 12 
490 0 |a CARDIOVASCULAR ULTRASOUND  |v 22 No. 1 
520 3 |a Atrial cardiomyopathy is closely associated with atrial fibrillation (AF), and some patients exhibit no dysfunction at rest but demonstrate evident changes in left atrial (LA) function and LA volume during exercise. This study aimed to identify distinguishing signs during exercise stress echocardiography (ESE) among patients in sinus rhythm (SR), with and without history of paroxysmal/persistent AF (PAF).A prospective cohort of 1055 patients in SR was enrolled across 12 centers. The main study cohort was divided into two groups: the modeling group (n = 513) and the verification group (n = 542). All patients underwent ESE, which included B-lines, LA volume index (LAVi), and LA strain of the reservoir phase (LASr).Age, resting and stress LAVi and LASr, and B-lines were identified as a combination of detectors for PAF in both groups. In the entire cohort, aside from resting and stress LAVi and LASr, additional parameters differentiating PAF and non-PAF patients were the presence of systemic hypertension, exercise E/e' > 7, worse right ventricle (RV) contraction during exercise (∆ tricuspid annular plane systolic excursion < 5 mm), a lower left ventricular contractile reserve (< 1.6), and a reduced chronotropic reserve (heart rate reserve < 1.64). The composite score, summing all 9 items, yielded a score of > 4 as the best sensitivity (79%) and specificity (65%).ESE can complement rest echocardiography in the identification of previous PAF in patients with SR through the evaluation of LA functional reservoir and volume reserve, LV chronotropic, diastolic, and systolic reserve, and RV contractile reserve. 
650 4 |a Klinikai orvostan 
700 0 1 |a Ciampi Quirino  |e aut 
700 0 1 |a Peteiro Jesus Vazquez  |e aut 
700 0 1 |a Kalinina Elena  |e aut 
700 0 1 |a Begidova Irina  |e aut 
700 0 1 |a Padang Ratnasari  |e aut 
700 0 1 |a Boshchenko Alla  |e aut 
700 0 1 |a Merli Elisa  |e aut 
700 0 1 |a Lisi Matteo  |e aut 
700 0 2 |a Rodriguez-Zanella Hugo  |e aut 
700 0 2 |a Kobal Sergio  |e aut 
700 0 2 |a Ágoston Gergely  |e aut 
700 0 2 |a Varga Albert  |e aut 
700 0 2 |a Wierzbowska-Drabik Karina  |e aut 
700 0 2 |a Kasprzak Jarosław D  |e aut 
700 0 2 |a Arbucci Rosina  |e aut 
700 0 2 |a Zhuravleva Olga  |e aut 
700 0 2 |a Čelutkienė Jelena  |e aut 
700 0 2 |a Lowenstein Jorge  |e aut 
700 0 2 |a Ratanasit Nithima Chaowalit  |e aut 
700 0 2 |a Colonna Paolo  |e aut 
700 0 2 |a Carerj Scipione  |e aut 
700 0 2 |a Pepi Mauro  |e aut 
700 0 2 |a Pellikka Patricia A  |e aut 
700 0 2 |a Picano Eugenio  |e aut 
700 0 2 |a Kollaborációs szervezet: Stress Echo 2030 study group  |e aut 
700 0 2 |a Pálinkás Attila  |e aut 
700 0 2 |a Sepp Róbert  |e aut 
700 0 2 |a Pálinkás Eszter Dalma  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/35119/1/Zagatina.pdf  |z Dokumentum-elérés