02878nab a2200325 i 4500 publ34777 20241219140817.0 241003s2024 hu o 000 eng d 2676-8615 10.1007/s42977-024-00227-1 doi 35089829 mtmt SZTE Publicatio Repozitórium hun eng Lantos Ferenc Investigation of in vitro biological activity of young Hordeum vulgare leaf in correlation with its bioactive compounds [elektronikus dokumentum] / Lantos Ferenc 2024 391-399 BIOLOGIA FUTURA 75 No. 4 Young shoots of cereals are widely regarded as superfoods with health benefits attributed to their potential antioxidant activity and antioxidant-related effects (e.g. anticancer). The current study aimed to examine the chemical characteristics of Hordeum vulgare methanolic and aqueous extracts and assess their antioxidant activity using the DDPH and ORAC. Furthermore, the inhibitory effect of xanthine oxidase was screened. TLC bioautography was employed to determine the polarity of the compounds present in the extracts that exhibited the most potent free radical scavenging activity. Total flavonoid content of the methanolic and aqueous extracts was 0.14 mg QE/g and 0.012 mg QE/g, respectively. The antioxidant activity of the methanolic extract was found to be more potent, with a value of 0.97 ± 0.13 mmol TE/g than the aqueous extract which had no activity. This study presents novel findings on the xanthine inhibitory activity of H. vulgare. The methanolic extract demonstrated moderate inhibition of xanthine oxidase with a value of 23.24%. The results of our study were compared with the phytochemical and pharmacological analysis of Triticum aestivum , and further comparison was made with the data reported in the literature. Inconsistencies were observed in the chemical and pharmacological properties of H. vulgare, which could be a result of using herbal material harvested in different vegetative phases and various methods used for extraction. The findings of our study indicate that the timing of the harvest and extraction method may play crucial role in attaining the optimal phytochemical composition of H. vulgare, hence enhancing its pharmacological activity. Általános orvostudomány Mezőgazdaság, erdészet, halászat Váczi Vivien aut Gyalai Ingrid aut Süli-Zakar Tímea aut Szarvas Adrienn aut Tar Melinda aut Püski Péter aut Bajtel Ákos aut Kiss Tivadar aut http://publicatio.bibl.u-szeged.hu/34777/1/InvestigationofinvitrobiologicalactivityofyoungHordeumvulgareleafincorrelationwithitsbioactivecompounds.pdf Dokumentum-elérés