Incident Cancer Risk of Patients with Prevalent Type 2 Diabetes Mellitus in Hungary (Part 2)
(1) Background: Among the chronic complications of type 2 diabetes mellitus, cancer has become the leading cause of death in several countries. Our objective was to determine whether prevalent type 2 diabetes mellitus is associated with a higher incidence of cancer. (2) Methods: This study comprised...
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2024
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| Sorozat: | CANCERS
16 No. 13 |
| Tárgyszavak: | |
| doi: | 10.3390/cancers16132414 |
| mtmt: | 35077393 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/34399 |
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| 100 | 2 | |a Abonyi-Tóth Zsolt | |
| 245 | 1 | 0 | |a Incident Cancer Risk of Patients with Prevalent Type 2 Diabetes Mellitus in Hungary (Part 2) |h [elektronikus dokumentum] / |c Abonyi-Tóth Zsolt |
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| 490 | 0 | |a CANCERS |v 16 No. 13 | |
| 520 | 3 | |a (1) Background: Among the chronic complications of type 2 diabetes mellitus, cancer has become the leading cause of death in several countries. Our objective was to determine whether prevalent type 2 diabetes mellitus is associated with a higher incidence of cancer. (2) Methods: This study comprised a nationwide analysis conducted in Hungary. The study population was divided into two groups: a type 2 diabetes mellitus group vs. a non-diabetic group. The primary outcome was the risk related to overall cancer incidence; a key secondary outcome was the overall incidence of cancer in distinct study years; and a further outcome was the annual percent changes. (3) Results: The odds ratio related to the overall incidence of cancer was 2.50 (95% confidence interval: 2.46–2.55, p < 0.0001) in patients with diabetes as related to non-diabetic controls. The odds ratio was higher in males than in females [ORmales: 2.76 (2.70–2.82) vs. ORfemales: 2.27 (2.22–2.33), p < 0.05 for male-to-female comparison]. The annual cancer incidence rate declined in non-diabetic controls, but not in patients with diabetes [−1.79% (−2.07–−1.52%), p < 0.0001] vs. −0.50% (−1.12–+0.10%), p = 0.0991]. Several types of cancer showed a decreasing tendency in non-diabetic controls, but not in patients with type 2 diabetes. (4) Conclusions: Type 2 diabetes is associated with a higher risk of cancer. While the cancer incidence decreased for non-diabetic individuals with time, it remained unchanged in patients with T2DM. | |
| 650 | 4 | |a Klinikai orvostan | |
| 700 | 0 | 1 | |a Rokszin György Aurél |e aut |
| 700 | 0 | 1 | |a Sütő Gábor |e aut |
| 700 | 0 | 2 | |a Bajcsayné Fábián Ibolya |e aut |
| 700 | 0 | 2 | |a Kiss Zoltán |e aut |
| 700 | 0 | 2 | |a Jermendy György |e aut |
| 700 | 0 | 2 | |a Kempler Péter |e aut |
| 700 | 0 | 2 | |a Lengyel Csaba Attila |e aut |
| 700 | 0 | 2 | |a Wittmann István |e aut |
| 700 | 0 | 2 | |a Molnár Gergő Attila |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/34399/1/Abonyi-Toth2.pdf |z Dokumentum-elérés |