Increasing the solubility characteristics of iomeglamic acid with β-cyclodextrin
Iomeglamic acid has been successfully applied for radioscopy of the gall-bladder since 1972. This pharmacon has the disadvantageous property that it is practically insoluble in water. Preparations containing the drug in different concentrations were made with β-cyclodextrin by different methods, and...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
1989
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| Sorozat: | JOURNAL OF INCLUSION PHENOMENA
7 No. 3 |
| Tárgyszavak: | |
| doi: | 10.1007/BF01076981 |
| mtmt: | 1912749 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/32750 |
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| 024 | 7 | |a 10.1007/BF01076981 |2 doi | |
| 024 | 7 | |a 1912749 |2 mtmt | |
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| 100 | 1 | |a Kata Mihály | |
| 245 | 1 | 0 | |a Increasing the solubility characteristics of iomeglamic acid with β-cyclodextrin |h [elektronikus dokumentum] / |c Kata Mihály |
| 260 | |c 1989 | ||
| 300 | |a 289-299 | ||
| 490 | 0 | |a JOURNAL OF INCLUSION PHENOMENA |v 7 No. 3 | |
| 520 | 3 | |a Iomeglamic acid has been successfully applied for radioscopy of the gall-bladder since 1972. This pharmacon has the disadvantageous property that it is practically insoluble in water. Preparations containing the drug in different concentrations were made with β-cyclodextrin by different methods, and their dissolution characteristics were determined. In the best situation the solubility increased ten-fold. The tablets were made from the most suitable complex, with β-cyclodextrin. The conditions of tableting, the parameters and the dissolution of the tablets were tested. © 1989 Kluwer Academic Publishers. | |
| 650 | 4 | |a Általános orvostudomány | |
| 700 | 0 | 1 | |a Aigner Zoltán |e aut |
| 700 | 0 | 1 | |a Révész Piroska |e aut |
| 700 | 0 | 1 | |a Selmeczi Béla |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/32750/1/aok_klny_302_89.pdf |z Dokumentum-elérés |