17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier
20-Hydroxyecdysone and several of its oxidized derivatives exert cytoprotective effect in mammals including humans. Inspired by this bioactivity of ecdysteroids, in the current study it was our aim to prepare a set of sidechain-modified derivatives and to evaluate their potential to protect the bloo...
Elmentve itt :
| Szerzők: |
Vágvölgyi Máté Laczkó Dávid Santa-Maria Ana Raquel Vigh Judit P. Walter Fruzsina R. Berkecz Róbert Deli Mária A. Tóth Gábor Hunyadi Attila |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2024
|
| Sorozat: | PLOS ONE
19 No. 2 |
| Tárgyszavak: | |
| doi: | 10.1371/journal.pone.0290526 |
| mtmt: | 34691003 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/29721 |
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