17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier

20-Hydroxyecdysone and several of its oxidized derivatives exert cytoprotective effect in mammals including humans. Inspired by this bioactivity of ecdysteroids, in the current study it was our aim to prepare a set of sidechain-modified derivatives and to evaluate their potential to protect the bloo...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Vágvölgyi Máté
Laczkó Dávid
Santa-Maria Ana Raquel
Vigh Judit P.
Walter Fruzsina R.
Berkecz Róbert
Deli Mária A.
Tóth Gábor
Hunyadi Attila
Dokumentumtípus: Cikk
Megjelent: 2024
Sorozat:PLOS ONE 19 No. 2
Tárgyszavak:
doi:10.1371/journal.pone.0290526

mtmt:34691003
Online Access:http://publicatio.bibl.u-szeged.hu/29721

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