The ubiquitin thioesterase YOD1 ameliorates mutant Huntingtin induced pathology in Drosophila
Huntington’s disease (HD) is a neurodegenerative disorder caused by a dominant gain-of-function mutation in the huntingtin gene, resulting in an elongated polyglutamine repeat in the mutant Huntingtin (mHtt) that mediates aberrant protein interactions. Previous studies implicated the ubiquitin–prote...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2023
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| Sorozat: | SCIENTIFIC REPORTS
13 No. 1 |
| Tárgyszavak: | |
| doi: | 10.1038/s41598-023-49241-8 |
| mtmt: | 34431874 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/29632 |