Thermodynamic Characterization of the Interaction of Biofunctionalized Gold Nanoclusters with Serum Albumin Using Two- and Three-Dimensional Methods
Fluorescent gold nanoclusters have been successfully used as fluorescent markers for imaging of cells and tissues, and their potential role in drug delivery monitoring is coming to the fore. In addition, the development of biosensors using structure-tunable fluorescent nanoclusters is also a promine...
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2023
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| Sorozat: | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
24 No. 23 |
| Tárgyszavak: | |
| doi: | 10.3390/ijms242316760 |
| mtmt: | 34406348 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/29477 |
| LEADER | 02378nab a2200277 i 4500 | ||
|---|---|---|---|
| 001 | publ29477 | ||
| 005 | 20240201135734.0 | ||
| 008 | 240201s2023 hu o 000 Angol d | ||
| 022 | |a 1661-6596 | ||
| 024 | 7 | |a 10.3390/ijms242316760 |2 doi | |
| 024 | 7 | |a 34406348 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a Angol | ||
| 100 | 1 | |a Juhász Ádám | |
| 245 | 1 | 0 | |a Thermodynamic Characterization of the Interaction of Biofunctionalized Gold Nanoclusters with Serum Albumin Using Two- and Three-Dimensional Methods |h [elektronikus dokumentum] / |c Juhász Ádám |
| 260 | |c 2023 | ||
| 300 | |a 11 | ||
| 490 | 0 | |a INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |v 24 No. 23 | |
| 520 | 3 | |a Fluorescent gold nanoclusters have been successfully used as fluorescent markers for imaging of cells and tissues, and their potential role in drug delivery monitoring is coming to the fore. In addition, the development of biosensors using structure-tunable fluorescent nanoclusters is also a prominent research field. In the case of these sensor applications, the typical goal is the selective identification of, e.g., metal ions, small molecules having neuroactive or antioxidant effects, or proteins. During these application-oriented developments, in general, there is not enough time to systematically examine the interaction between nanoclusters and relevant biomolecules/proteins from a thermodynamic viewpoint. In this way, the primary motivation of this article is to carry out a series of tests to partially fill this scientific gap. Besides the well-known fluorescent probes, the mentioned interactions were investigated using such unique measurement methods as surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC). These two-dimensional (at the solid/liquid interface) and three-dimensional (in the bulk phase) measuring techniques provide a unique opportunity for the thermodynamic characterization of the interaction between different gold nanoclusters containing various surface functionalizing ligands and bovine serum albumin (BSA). | |
| 650 | 4 | |a Kémiai tudományok | |
| 700 | 0 | 1 | |a Gombár Gyöngyi |e aut |
| 700 | 0 | 2 | |a F. Várkonyi Egon |e aut |
| 700 | 0 | 2 | |a Wojnicki Marek |e aut |
| 700 | 0 | 2 | |a Ungor Ditta |e aut |
| 700 | 0 | 2 | |a Csapó Edit |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/29477/1/ijms_Juhasz_clustersinteraction.pdf |z Dokumentum-elérés |