Myocardial, Valvular, and Vascular Structural and Functional Properties in Acromegaly

Acromegaly is an uncommon systematic endocrine disease caused by the hypersecretion of human growth hormone and, consequently, of insulin-like growth factor-1 during adulthood. Acromegaly could cause a typical cardiomyopathy characterized by left ventricular hypertrophy associated with diastolic dys...

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Bibliographic Details
Main Authors: Nemes Attila
Kormányos Árpád
Ambrus Nóra
Lengyel Csaba Attila
Valkusz Zsuzsanna
Format: Article
Published: 2023
Series:JOURNAL OF CLINICAL MEDICINE 12 No. 21
Subjects:
doi:10.3390/jcm12216857

mtmt:34227610
Online Access:http://publicatio.bibl.u-szeged.hu/28549
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520 3 |a Acromegaly is an uncommon systematic endocrine disease caused by the hypersecretion of human growth hormone and, consequently, of insulin-like growth factor-1 during adulthood. Acromegaly could cause a typical cardiomyopathy characterized by left ventricular hypertrophy associated with diastolic dysfunction, which later could progress to systolic dysfunction. Moreover, some valvular and vascular abnormalities are also associated with acromegaly. This present review aims to summarize available information regarding acromegaly-associated abnormalities in myocardial, valvular, and vascular structural and functional properties and their relationship to disease activity and treatment options. 
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