Significant improvement in melanoma survival over the last decade A Hungarian nationwide study between 2011 and 2019 /

Recent real-world studies have reported significant improvements in the survival of malignant melanoma in the past few years, mainly as a result of modern therapies. However, long-term survival data from Central Eastern European countries such as Hungary are currently lacking.This nationwide, retros...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Liszkay Gabriella
Benedek Angela
Polgár Csaba
Oláh Judit Magdolna
Holló Péter
Emri Gabriella
Csejtei András
Kenessey István
Polányi Zoltán
Knollmajer Kata
Várnai Máté
Vokó Zoltán
Nagy Balázs
Rokszin György Aurél
Bajcsayné Fábián Ibolya
Barcza Zsófia
Gyulai Rolland Péter
Kiss Zoltán
Dokumentumtípus: Cikk
Megjelent: 2023
Sorozat:JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 37 No. 5
Tárgyszavak:
doi:10.1111/jdv.18960

mtmt:33647469
Online Access:http://publicatio.bibl.u-szeged.hu/28532
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520 3 |a Recent real-world studies have reported significant improvements in the survival of malignant melanoma in the past few years, mainly as a result of modern therapies. However, long-term survival data from Central Eastern European countries such as Hungary are currently lacking.This nationwide, retrospective study examined melanoma survival in Hungary between 2011-2019 using the databases of the National Health Insurance Fund (NHIF) and Central Statistical Office (CSO) of Hungary. Crude overall survival and age-standardized 5-year net survival as well as the association between age, sex, and survival were calculated.Between 2011 and 2019, 22,948 newly diagnosed malignant melanoma cases were recorded in the NHIF database (47.89% male, mean age: 60.75 years (SD: ±16.39)). 5-year overall survival was 75.40% (women: 80.78%; men: 69.52%). Patients diagnosed between 2017-2019 had a 20% lower risk of mortality compared to patients diagnosed between 2011-2012 (HR 0.80, 95% CI 0.73-0.89; p<0.0001). Age-standardized 5-year net survival rates in 2011-2014 and 2015-2019 were 90.6% and 95.8%, respectively (women: 93.1% and 98.4%, men: 87.8% and 92.7%, respectively). The highest age-standardized 5-year net survival rates were found in the 0-39 age cohort (94.6% in the 2015-2019 period).Hungary has similar melanoma survival rates to Western European countries. Based on net survival, the risk of dying of melanoma within 5 years was cut by more than half (55%) during the study period, which coincides with the successful implementation of awareness campaigns and the wide availability of modern therapies. 
650 4 |a Klinikai orvostan 
700 0 1 |a Benedek Angela  |e aut 
700 0 1 |a Polgár Csaba  |e aut 
700 0 1 |a Oláh Judit Magdolna  |e aut 
700 0 1 |a Holló Péter  |e aut 
700 0 1 |a Emri Gabriella  |e aut 
700 0 1 |a Csejtei András  |e aut 
700 0 1 |a Kenessey István  |e aut 
700 0 1 |a Polányi Zoltán  |e aut 
700 0 1 |a Knollmajer Kata  |e aut 
700 0 1 |a Várnai Máté  |e aut 
700 0 1 |a Vokó Zoltán  |e aut 
700 0 1 |a Nagy Balázs  |e aut 
700 0 1 |a Rokszin György Aurél  |e aut 
700 0 2 |a Bajcsayné Fábián Ibolya  |e aut 
700 0 2 |a Barcza Zsófia  |e aut 
700 0 2 |a Gyulai Rolland Péter  |e aut 
700 0 2 |a Kiss Zoltán  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/28532/1/AcadDermatolVenereol-2023-Liszkay-SignificantimprovementinmelanomasurvivaloverthelastdecadeAHungarian.pdf  |z Dokumentum-elérés