Selective Inhibition of Cardiac Late Na+ Current Is Based on Fast Offset Kinetics of the Inhibitor
The present study was designed to test the hypothesis that the selectivity of blocking the late Na+ current (INaL) over the peak Na+ current (INaP) is related to the fast offset kinetics of the Na+ channel inhibitor. Therefore, the effects of 1 µM GS967 (INaL inhibitor), 20 µM mexiletine (I/B antiar...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2023
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| Sorozat: | BIOMEDICINES
11 No. 9 |
| Tárgyszavak: | |
| doi: | 10.3390/biomedicines11092383 |
| mtmt: | 34113182 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/28120 |