Protein kinase c activation in aplysia neurons by phorbol diacetate comparison of effects following extracellular or intracellular application /
The effects of protein kinase C activation on electrophysiological phenomena of neurons in Aplysia californica ganglions were studied. The enzyme was activated by phorbol-12,13-diacetate applied either extracellularly by perfusion, or by intracellular pressure injection. In both forms of application...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
1993
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| Sorozat: | ACTA PHYSIOLOGICA HUNGARICA
81 No. 2 |
| Tárgyszavak: | |
| mtmt: | 1240484 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/27599 |
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| 024 | 7 | |a 1240484 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a Angol | ||
| 100 | 1 | |a Papp András | |
| 245 | 1 | 0 | |a Protein kinase c activation in aplysia neurons by phorbol diacetate |h [elektronikus dokumentum] : |b comparison of effects following extracellular or intracellular application / |c Papp András |
| 260 | |c 1993 | ||
| 300 | |a 147-157 | ||
| 490 | 0 | |a ACTA PHYSIOLOGICA HUNGARICA |v 81 No. 2 | |
| 520 | 3 | |a The effects of protein kinase C activation on electrophysiological phenomena of neurons in Aplysia californica ganglions were studied. The enzyme was activated by phorbol-12,13-diacetate applied either extracellularly by perfusion, or by intracellular pressure injection. In both forms of application, an increase in the potential upstroke speed and amplitude as well as a reduction of the depolarization evoked by extracellular acetylcholine application was found. A protein kinase C blocker, H-7, had opposite effects on the action potential. All observed actions of the phorbol ester were consistently faster in intracellular application than extracellular. | |
| 650 | 4 | |a Biológiai tudományok | |
| 650 | 4 | |a Általános orvostudomány | |
| 700 | 0 | 1 | |a Klee M. R. |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/27599/1/PappA-Klee-ActaPhysHu.pdf |z Dokumentum-elérés |