Factors influencing successful reconstruction of tympanic membrane perforations a systematic review and meta-analysis /

Based on a systematic review and meta-analysis, our study aimed to provide information about the factors that influence the success of tympanic membrane reconstruction.Our systematic search was conducted on November 24, 2021, using the CENTRAL, Embase, and MEDLINE databases. Observational studies wi...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Illés Kata
Gergő Dorottya
Keresztély Zsuzsanna
Dembrovszky Fanni
Fehérvári Péter
Bánvölgyi András
Csupor Dezső
Hegyi Péter
Horváth Tamás
Dokumentumtípus: Cikk
Megjelent: 2023
Sorozat:EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY 280 No. 6
Tárgyszavak:
doi:10.1007/s00405-023-07831-2

mtmt:33662217
Online Access:http://publicatio.bibl.u-szeged.hu/26998
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490 0 |a EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY  |v 280 No. 6 
520 3 |a Based on a systematic review and meta-analysis, our study aimed to provide information about the factors that influence the success of tympanic membrane reconstruction.Our systematic search was conducted on November 24, 2021, using the CENTRAL, Embase, and MEDLINE databases. Observational studies with a minimum of 12 months of follow-up on type I tympanoplasty or myringoplasty were included, while non-English articles, patients with cholesteatoma or specific inflammatory diseases, and ossiculoplasty cases were excluded. The protocol was registered on PROSPERO (registration number: CRD42021289240) and PRISMA reporting guideline was used. Risk of bias was evaluated with the QUIPS tool. A random effect model was used in the analyses. Primary outcome was the rate of closed tympanic cavities.After duplicate removal, 9454 articles were found, of which 39 cohort studies were included. Results of four analyses showed significant effects: age (OR: 0.62, CI 0.50; 0.78, p value: 0.0002), size of the perforation (OR: 0.52, CI 0.29; 0.94, p value: 0.033), opposite ear condition (OR: 0.32, CI 0.12; 0.85, p value: 0.028), and the surgeon's experience (OR: 0.42, CI 0.26; 0.67, p value: 0.005), while prior adenoid surgery, smoking, the site of the perforation, and discharge of the ear did not. Four factors: etiology, Eustachian tube function, concomitant allergic rhinitis, and duration of the ear discharge were analyzed qualitatively.The age of the patient, the size of the perforation, the opposite ear status, and the surgeon's experience have a significant effect on the success of tympanic membrane reconstruction. Further comprehensive studies are needed to analyze the interactions between the factors.Not applicable. 
650 4 |a Farmakológia és gyógyszerészet 
700 0 1 |a Gergő Dorottya  |e aut 
700 0 1 |a Keresztély Zsuzsanna  |e aut 
700 0 1 |a Dembrovszky Fanni  |e aut 
700 0 1 |a Fehérvári Péter  |e aut 
700 0 1 |a Bánvölgyi András  |e aut 
700 0 1 |a Csupor Dezső  |e aut 
700 0 1 |a Hegyi Péter  |e aut 
700 0 1 |a Horváth Tamás  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/26998/3/33662217_megjelent.pdf  |z Dokumentum-elérés  
856 4 0 |u http://publicatio.bibl.u-szeged.hu/26998/1/EurArcORL2023IllesKFactorsmeta.pdf  |z Dokumentum-elérés