Thiopurines impair the apical plasma membrane expression of CFTR in pancreatic ductal cells via RAC1 inhibition
Thiopurine-induced acute pancreatitis (TIP) is one of the most common adverse events among inflammatory bowel disease patients treated with azathioprine (AZA), representing a significant clinical burden. Previous studies focused on immune-mediated processes, however, the exact pathomechanism of TIP...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2023
|
| Sorozat: | CELLULAR AND MOLECULAR LIFE SCIENCES
80 No. 1 |
| Tárgyszavak: | |
| doi: | 10.1007/s00018-022-04662-y |
| mtmt: | 33546837 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/26125 |