Aconitum Alkaloid Songorine Exerts Potent Gamma-Aminobutyric Acid-A Receptor Agonist Action In Vivo and Effectively Decreases Anxiety without Adverse Sedative or Psychomotor Effects in the Rat

Songorine (SON) is a diterpenoid alkaloid from Aconitum plants. Preparations of Aconitum roots have been employed in traditional oriental herbal medicine, however, their mechanisms of action are still unclear. Since GABA-receptors are possible brain targets of SON, we investigated which subtypes of...

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Bibliographic Details
Main Authors: Bali Zsolt Kristóf
Bruszt Nóra
Kőszegi Zsombor
Nagy Lili Veronika
Atlasz Tamás
Kovács Péter
Csupor Dezső
Csupor-Löffler Boglárka
Hernádi István
Format: Article
Published: 2022
Series:PHARMACEUTICS 14 No. 10
Subjects:
doi:10.3390/pharmaceutics14102067

mtmt:33117614
Online Access:http://publicatio.bibl.u-szeged.hu/26074

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